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Supports efforts to develop and optimize evidence-based treatments for soldiers and civilians suffering from amputations, traumatic brain injuries, and neurological disorders such as epilepsy. A distinguishing feature of this interdisciplinary project is the use of techniques ranging from state-of-the-art brain imaging (functional and structural MRI and dense array EEG) to genetic and behavioral analyses, to advanced computational modeling. These combined capabilities are the foundation to increase the ability to harness the brain’s remarkable capacity to respond adaptively to change, also know as neuroplasticity, including responses to bodily (e.g., amputation) or brain (e.g., TBI or stroke) injuries, as well as to stimulation provided by effective therapeutic interventions. Neuroplasticity is widely regarded as the basis for recovery of function and yet the field of neurorehabilitation remains hampered by a relative lack of interventions that are grounded in neuroscientific evidence. Previous research has identified a number of factors that influence neuroplasticity, and the current project is translating these basic research findings into more effective and efficient diagnostic and interventional practices. Funds would build upon past years of funding and the well-established partnership with the Department of the Army’s Telemedicine and Advanced Technology Research Center.
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